Foundation Funds Follow-up Care in Revolutionary Cancer Vaccine Study

Onyx and Breezy Foundation Funds Follow-up Care in Revolutionary Cancer Vaccine Study

The Onyx & Breezy Foundation recently funded after-care for dogs engaged in a revolutionary research study to develop a cancer vaccine that may be given to both humans and animals when successful. The study is being conducted at The Matthew J. Ryan Veterinary Hospital, a small animal teaching hospital affiliated with the University of Pennsylvania in Philadelphia.

Tuxedo Park, NY and Philadelphia, PA  -  March 14 -- The Onyx & Breezy Foundation has announced a gift to The University of Pennsylvania School of Veterinary Medicine. The gift will cover the expense of follow-up care for 12 dogs that are currently enrolled in the School's cancer vaccine study.

"Thanks to this generous gift, more participants in our lymphoma cancer vaccine clinical trial will be able to return for follow-up care," said Dr. Karin Sorenmo, chief of oncology at the Matthew J. Ryan Veterinary Hospital. "This means that we can capture all the data that is needed for the study while pet owners are helped financially."

Prior gifts to The Matthew J. Ryan Veterinary Hospital from the Foundation have been a respirator for their ICU department and a mast cell tumor research study.

Dr. Sorenmo treated Breezy, who had mast cell tumors. "Thanks to Dr. Sorenmo, Breezy lived another 2 years, of quality life, after other vets gave her only 6 weeks to live," said Wanda Shefts. "We are glad that this project will help owners of dogs in remission from lymphoma and help advance Dr. Sorenmo's work on the cancer vaccine.

Dr. Sorenmo stated that she was encouraged by the results and she is hoping that this is just the beginning of more trials that can benefit dogs and ultimately help people. Thanks to this study, a number of the participating dogs are now cancer free. The researchers now estimate that they are within two years of testing the vaccine on humans. Without the dogs, they would be more than a decade away.

"We have a tremendous amount of respect for the work they do at the Hospital and we are glad to be able to fund another project for them", said Mark Shefts.

For more information about Penn Vet, please visit www.vet.upenn.edu; for more information about The Onyx and Breezy Foundation, please visit www.onyxandbreezy.org.

The Onyx and Breezy Foundation Background

The Foundation was created in 2004 and named after the trustees Mark & Wanda Shefts' two Labrador Retrievers. The Foundation lends financial support to organizations that benefit the welfare of animals.

The University Of Pennsylvania School Of Veterinary Medicine Background

Penn's School of Veterinary Medicine is one of the world's premier veterinary schools. Founded in 1884, the School was built on the concept of Many Species, One MedicineTM. The birthplace of veterinary specialties, the School serves a distinctly diverse array of animal patients, from pets to horses to farm animals.

Press Contact: Barbara Kauffman
Company Name: The Onyx & Breezy Foundation
Phone: 201-782-7400
Website: www.onyxandbreezy.org

New, Flexible Individual Health Insurance Plans

HumanaOne Introduces New, Flexible Individual Health Insurance Plans in Nine States

Individual insurance plans from HumanaOne meet a wide range of consumer needs.

Louisville, KY  -  March 11 -- Humana (NYSE: HUM) today announced the introduction of a new portfolio of individual health insurance plans under its HumanaOne® brand in nine states -- Alabama, Arkansas, Iowa, Indiana, Mississippi, Nebraska, Oklahoma, South Carolina and Utah. In 2007, Humana introduced the individual health insurance coverage options in 15 other states (listed below), where they have been popular with consumers.

The variety of plans makes it easy for individuals and families to select a plan according to their own personal preferences, lifestyles and budgets. HumanaOne plans are designed specifically for self-employed entrepreneurs, small-business employees, part-time workers, students and early retirees. Humana markets HumanaOne plans through insurance agents and brokers, as well as directly to consumers. Health insurance quote applications for the plans are available online or by phone.

HumanaOne's new personal health insurance plan portfolio includes a broad spectrum of benefits -- with three in-network coinsurance levels and 17 annual deductible choices -- organized into three, distinct packages, for:

•    People who are security-minded and want benefits like those provided by big employers
•    People who want flexibility to fit their financial plan, including HSA-qualified offerings
•    People who want a low-cost plan with a safety net "just in case"

The plans can be further customized with optional benefits such as dental insurance, life insurance, and supplemental accident coverage.

"With the U.S. market for individual health insurance at 18 million and growing, we recognize that individual health insurance plans cannot be 'one size fits all,'" said Jerry Ganoni, president of HumanaOne, Humana Small Business and HumanaDental. "That's why we created three separate families of plans, each tailored for a particular kind of consumer, but at the same time highly customizable. This represents the most significant product expansion for HumanaOne since its inception in 2002."

In 2007, Humana launched the new products in 15 other states -- Arizona, Colorado, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Missouri, North Carolina, Ohio, Tennessee, Texas and Wisconsin. Soon, the company plans to introduce the new product portfolio in the remaining two states where HumanaOne currently operates. At present, HumanaOne serves more than 250,000 health plan members in 26 states.

The new plans from HumanaOne are designed to appeal to a variety of consumers -- from those who desire the security, coverage and service commonly found in health plans from large employers, to those wanting a simple safety net in the event of a major health problem.

The new portfolio of HumanaOne plans offers deductibles ranging from $1,000 to $7,500 for single coverage, and from $2,000 to $15,000 for family coverage. Premiums start as low as $30 per month for single coverage and increase according to the plan, its features and level of benefits.

"This new portfolio of products positions HumanaOne to serve a much larger portion of the individual health insurance market, which we believe will continue to grow at a rate of five to eight percent annually over the next five years," said Steve DeRaleau, chief operating officer of HumanaOne. "As more people leave group health plans, retire early, become self-employed or work part-time, they will increasingly look to individual health plans, and HumanaOne will be there to serve them with a plan ideally suited to their distinct needs."

Humana guarantees monthly premium rates on its HumanaOne plans for one full year after purchase, as long as the member remains in the same area and keeps the same benefits. Thanks to Humana's large network of doctors and hospitals, HumanaOne policyholders who move to a different state can simply take their plan with them, and in most cases, those who work or travel away from home can receive in-network benefits by seeing any of the more than 400,000 Humana-contracted doctors, hospitals and other health care providers across the country.

HumanaOne members have 24-hour access to online tools and resources, enabling them to check claims status, medical expenses, compare hospital, doctor and prescription costs and more. HumanaOne accepts applications by phone or via its Website at http://www.humana-one.com/.

About Humana

Humana Inc., headquartered in Louisville, Kentucky, is one of the nation's largest publicly traded health and supplemental benefits companies, with approximately 11.5 million medical members. Humana is a full-service benefits solutions company, offering a wide array of health and supplementary benefit plans for employer groups, government programs and individuals.

Over its 47-year history, Humana has consistently seized opportunities to meet changing customer needs. Today, the company is a leader in consumer engagement, providing guidance that leads to lower costs and a better health plan experience throughout its diversified customer portfolio.

More information regarding Humana is available to investors via the Investor Relations page of the company's web site at Humana.com, including copies of:
•    Annual reports to stockholders
•    Securities and Exchange Commission filings
•    Most recent investor conference presentations
•    Quarterly earnings news releases
•    Replays of most recent earnings release conference calls
•    Calendar of events (includes upcoming earnings conference call dates and times, as well as planned interaction with research analysts and institutional investors)
•    Corporate Governance Information

Press Contact: Jim Turner
Company Name: HumanaOne
Phone: 502-476-2119
Website: http://www.humana-one.com/

Suboxone Treatment Program Launched

InterventionTreatment.com Launches Suboxone Treatment Program

LOS ANGELES-- June 27, 2008 --Intervention Treatment announced today that it has launched a suboxone treatment program. The program will be used to increase Intervention Treatment's Global mission of providing Intervention and Treatment resources to those affected by alcohol and drug addiction. According to Dr. Jason Schiffman, Chief Medical Officer for Intervention Treatment, "There is a large, poorly met demand for outpatient, office-based treatment of opiate dependence and the addition of the suboxone treatment program to Intervention Treatment's array of alcohol and drug addiction related services will be a great tool for patients and their families."

Intervention Treatment is currently one of the fastest growing online resources for those affected by drug and alcohol addiction. The new Suboxone Treatment program is designed to help those affected by opiate addiction.

About Suboxone:

Suboxone is the first drug approved by the FDA for opiate dependence treatment in office based settings. This means that patients addicted to opiates may now choose to receive opiate-based treatment as an outpatient instead of in a hospital setting. Patients are evaluated and treated during office visits and receive a prescription for suboxone which they may fill at any pharmacy. Suboxone is comprised of two separate medications: buprenorphine and naloxone. Buprenorphine is a partial opiate agonist, meaning its opiate effects are significantly reduced compared to that of full opiate agonists, such as vicodin or heroin. The naloxone in suboxone is not appreciably absorbed from the digestive track when suboxone is taken orally and is in place to prevent the misuse of suboxone by injection drug users. The combination of these two medications leads to suboxone's effectiveness in treating opiate dependence.

About Suboxone Treatment:

Suboxone treatment differs significantly from standard opiate dependence treatment programs. Traditionally, opiate addicts undergoing medical detoxification have been administered either methadone or a combination of drugs, each targeting a symptom of withdrawal. The latter approach usually must take place in an inpatient setting in order to be done safely, while methadone treatment requires a patient to visit a clinic on a daily basis to receive a prescribed dose. Suboxone treatment differs from these treatments in several important ways. Firstly, a prescription for suboxone can be obtained at a specially licensed physician's office and filled at any pharmacy. This means the patient does not need to be admitted to a hospital or make daily visits to a methadone clinic in order to receive their medication. Secondly, because suboxone is a mixture of naloxone and buprenorphine, a partial opiate agonist with a long duration of action, the potential for abuse and overdose are much less than with methadone. Thirdly, because buprenorphine is a partial opiate agonist, suboxone may be easier to taper off of than full opiate agonists like methadone.

About Intervention Treatment

Intervention Treatment, formed in 2007, is an internet resource offering help to those affected by drug and alcohol addiction. Intervention Treatment provides referrals to drug and alcohol rehabs, intervention services, suboxone treatment referrals, and general information regarding addiction and treatment.

Safe Harbor Statement

This press release contains statements that may constitute "forward-looking statements" within the meaning of the Securities Act of 1933 and the Securities Exchange Act of 1934, as amended by the Private Securities Litigation Reform Act of 1995. Those statements include statements regarding the intent, belief or current expectations of the Company, and members of their management as well as the assumptions on which such statements are based. Prospective investors are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those contemplated by such forward-looking statements. Important factors currently known to management that could cause actual results to differ materially from those in forward-statements include fluctuation of operating results, the ability to compete successfully and the ability to complete before-mentioned transactions. The company undertakes no obligation to update or revise forward-looking statements to reflect changed assumptions, the occurrence of unanticipated events or changes to future operating results.
Contacts

Intervention Treatment
William Donovan, Co-Founder, 949-267-4113
bj@interventiontreatment.com
www.interventiontreatment.com

Baxter Heparin Information on Additional Heparin Recall

LegalView Expands Baxter Heparin Information Portal to Include Information on an Additional Heparin Recall

LegalView updated its Baxter Heparin information portal to add information on the most recent recall of the blood-thinning drug. Heparin, which is used to control blood during surgical procedures, was recently discovered to have a Heparin-like contaminant that sickened many and caused at least 19 deaths.

Denver, CO  -  March 31, 2008 -- The Baxter Heparin practice area on LegalView's site, the source for everything legal on the Web, was recently expanded to explain details of an additional Heparin recall . Heparin has been linked to hundreds of allergic reactions among patients as well as having been connected with 19 deaths. B. Braun Medical Inc. issued the most recent recall of Heparin, which was supplied from Scientific Protein Laboratories - the same company that supplied Baxter Healthcare Corporation with the contaminated Baxter Heparin. According to the U.S. Food and Drug Administration (FDA) and B. Braun Medical Inc., no one was reportedly sickened off of the Heparin from B. Braun Medical but it did have a "heparin-like contaminant," which was enough for the company to recall the drug.

Heparin is blood-thinner injected into patients who are undergoing surgical procedures such as heart disease or kidney dialysis. It is a drug that has been imported to the United States since the 1930s and is derived from pig intestines. Many surgeons find that Heparin is an extremely important drug because it prevents blood clots from forming during surgery, which can result in death among patients. However, earlier this year, a rash of individuals who had been given Heparin during a surgical procedure had allergic reactions. Individuals who have been affected by the contaminated Heparin should consider contacting a Heparin lawyer to learn about developing a Heparin class action lawsuit for which compensation may be derived from manufacturers if the tainted drug.

The Baxter Heparin that was initially recalled had been tainted with a chemical known as over-sulfated chondroitin sulfate. Through an FDA investigation, it was discovered that a Chinese company that produces the drug was responsible for the tainted Heparin. Although an investigation continues to be ongoing as to whether the chemical was intentionally or accidentally introduced into a batch of the Heparin. According to news reports, using the over-sulfated chondroitin sulfate allows for a reduction in the production of production for Heparin.

For information on additionally recalled prescription drugs or to report an adverse reaction to a prescribed drug, visit LegalView's many unsafe drugs information portals. Here, readers will find information on recently recalled drugs as well as prescription drugs under investigation such as Chantix, Avandia and Trasylol Aprotinin.

Chantix is a smoking cessation drug from Pfizer that was first introduced to the market, with FDA approval, in mid-2006. However, in late-2007 the FDA began an investigation into nearly 400 reports of suicidal tendencies and behaviors among patients. Additionally, nearly 37 suicides have been associated with the Chantix side effects, which include psychotic episodes, depression, suicidal thoughts and erratic behavior.

Avandia is a prescription drug used to treat diabetes 2 among patients; however, the drug has been linked to several serious side effects including an increased risk of heart disease and a higher chance of early onset osteoporosis. Individuals who are taking Avandia are advised to locate an experienced pharmaceutical law firm to receive consultation on an Avandia lawsuit.

Trasylol, also known as its generic version Aprotinin, is similar to Heparin in that it is used during surgical procedures to control blood loss. A study was released in 2006 from the New England Journal of Medicine, which found that the use of Trasylol Aprotinin increased the chances of a patient developing heart disease, kidney disease, stroke and death. Patients who received or may have received Trasylol or it's generic version should use LegalView's information portal to find an Trasylol attorney.

About LegalView:
LegalView.com is a public service brought to you by Legal WebTV Network, LLC, a Limited Liability Corporation created by a group of the nation's most highly respected law firms: Anapol Schwartz; Brent Coon and Associates; Burg Simpson; Cohen, Placitella and Roth; James F. Humphreys and Associates; Lopez McHugh; and Thornton and Naumes. For more information on the accomplishments and track records of LegalView.com's superior sponsoring law firms and to get in touch with LegalView attorneys, visit LegalView at www.LegalView.com.

Press Contact: Katie Kelley
Company Name: LegalView
Phone: 720-771-3246
Website: http://baxter-heparin.legalview.com

Medical Device Enables Minimally-Invasive Treatment

FDA Approves Medtronic's Talent Abdominal Stent Graft for Repairing Aortic Aneurysms

Innovative Medical Device Enables Minimally-Invasive Treatment of Potentially Fatal Condition

MINNEAPOLIS--April 16, 2008--Medtronic, Inc. (NYSE: MDT), today announced approval from the U.S. Food and Drug Administration for use of the TalentT Abdominal Stent Graft on the CoilTrac Delivery System, an innovative medical device that expands patient access to a minimally-invasive treatment option for abdominal aortic aneurysms.

Present in an estimated 1.2 million people and responsible for approximately 15,000 annual deaths in the United States, an abdominal aortic aneurysm (AAA) is a dangerous bulge or weakening of the body's main artery that can rupture with fatal consequences if left untreated. Ruptured AAAs are currently the 10th leading cause of death among U.S. men over age 55, with fewer than 20 percent of people surviving a rupture. But early detection through painless ultrasound screening and minimally invasive treatment with a technique called endovascular repair (EVAR) have historically shown a significant improvement in the survival rate for patients of all ages.

"This important milestone demonstrates Medtronic's leadership and commitment to the field of aortic repair," said Katie Szyman, vice president and general manager of the Endovascular Innovations business at Medtronic. "Endovascular interventionalists in the United States now have access to the broadest portfolio of stent grafts for the treatment of their AAA patients. The Talent Abdominal System significantly increases the number of AAA patients who can benefit from minimally-invasive repair. As an alternative to open surgical repair, this device will save the lives of many people affected by abdominal aortic aneurysmal disease."

Expanding Indication for EVAR

The Talent Abdominal Stent Graft System makes endovascular repair (EVAR) accessible to an additional 20 percent of AAA patients, because of its unique proximal aortic neck length requirement of only 10 mm. Consisting of a woven polyester membrane supported by a tubular metal lattice, the device is specifically indicated for endovascular treatment of abdominal aortic aneurysms with or without iliac involvement. The stent graft is available in diameters of up to 36 mm, as well as flared and tapered iliac limbs of 8 mm to 24 mm.

With a 12-year history of strong clinical performance including more than 45,000 implants worldwide, the Talent Abdominal Stent Graft is designed to offer broad patient applicability, suprarenal fixation and positioning accuracy. The stent graft features radiopaque markers for visual guidance during deployment and follow up, and the delivery system uses a single-step release mechanism for smooth deployment and a coiled rod for enhanced trackability and flexibility.

"The Talent Abdominal Stent Graft has provided excellent patient outcomes in clinical practice and in clinical study," said Dr. Michael L. Marin, professor of Vascular Surgery and chairman of the Department of Surgery at The Mount Sinai Medical Center in New York. "In my own experience, with more than 750 successful implants using the Talent System, the performance of this stent graft has been very consistent, and its safety and efficacy have been well characterized through the results of our own clinical trial."

Advantages Over Open Repair

The Medtronic-sponsored clinical study of the Talent Abdominal Stent Graft System enrolled 166 patients at 13 medical centers between February 2002 and April 2003. All 166 patients received a Talent Abdominal Stent Graft; their outcomes were compared to those of 243 patients from the Society of Vascular Surgery (SVS) Surgical Control Group at 30 days and one year post-implant. Dr. Frank Criado, director of Union Memorial Hospital's Endovascular Program in Baltimore, was the principal investigator for the study.

The study demonstrated that the Talent Abdominal Stent Graft well exceeded the SVS Control in freedom from major adverse events at 30 days, with a statistically significant difference between the two groups: Talent, 89.2%; SVS Control, 44.0%. Although patients receiving the Talent Abdominal Stent Graft were older and had a higher baseline rate of co-morbidities, at 30 days post-implant they experienced lower rates of major adverse events compared with subjects treated with open surgery. Importantly, there were no aneurysm ruptures and no conversions to open surgery in the Talent group up to 12 months after device implantation.

"As Talent is already the leading stent graft for endovascular treatment of AAAs outside the United States, its approval by the FDA is a most welcome and exciting development," Dr. Criado said. "AAA patients in this country can now enjoy the benefits of this device, which has been shown in the pivotal clinical trial to have distinct advantages over standard surgical treatment."

In previous studies, EVAR has been shown to be an effective therapy for AAA, with fewer postoperative complications and shorter recovery times than open surgical repair. Results from a U.S. study published recently in The New England Journal of Medicine (Jan. 31, 2008), for example, indicate that perioperative mortality was significantly lower after EVAR than after open repair: 1.2 percent vs. 4.8 percent - a fourfold difference. Similarly, in a landmark study conducted in the United Kingdom and published in The Lancet (Sept. 4, 2004), the 30-day mortality rate for EVAR patients was 1.7 percent compared to 4.7 percent for patients who underwent open repair - a nearly threefold difference.

Although AAAs typically produce no symptoms until rupturing, they can be detected through a simple, painless and inexpensive ultrasound screening, which is offered free-of-charge to new Medicare beneficiaries. If detected before rupturing, AAAs with diameters of more than twice the size of the normal infrarenal aorta are typically treated with either open surgical repair or endovascular repair (EVAR). In contrast to open surgical repair, EVAR involves a minimally invasive procedure in which a stent graft is threaded through the femoral artery in a compressed state on a delivery system and expanded inside the aorta at the site of the aneurysm. Once in place, the stent graft creates a new path for blood flow, reducing pressure on the aneurysm.

As a pioneer of endovascular therapy development, Medtronic has been an innovator and leader in the endovascular stent graft industry for more than a decade, as evidenced by more implants than any other company. Its long history includes more than 130,000 patients treated with stent grafts dating back to 1995. Medtronic currently offers the broadest portfolio of endovascular stent grafts in the industry. These include the AneuRx AAAdvantage® and Talent Abdominal Stent Graft Systems in the United States, and the Talent Abdominal, Talent Thoracic and Valiant® Thoracic Stent Graft Systems outside the United States.

About Medtronic

Medtronic, Inc. (www.medtronic.com), headquartered in Minneapolis, is the global leader in medical technology - alleviating pain, restoring health, and extending life for millions of people around the world.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's Annual Report on Form 10-K for the year ended April 27, 2007. Actual results may differ materially from anticipated results.

Contacts

Medtronic, Inc.
Public Relations
Joe McGrath, 707-591-7367
or
Investor Relations
Jeff Warren, 763-505-2696

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